Molecule Details
| InChIKey | LOYHRPQPVDZCBA-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one |
| Canonical SMILES | Cc1cccc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.31 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P33261 | CYP2C19 | Homo sapiens | Human | PF00067 | 6.6 | IC50 | ChEMBL |
| P05177 | CYP1A2 | Homo sapiens | Human | PF00067 | 6.4 | IC50 | ChEMBL;BindingDB |
| P08684 | CYP3A4 | Homo sapiens | Human | PF00067 | 6.2 | IC50 | ChEMBL;BindingDB |
| P08069 | IGF1R | Homo sapiens | Human | PF00757 PF07714 PF01030 | 6.1 | IC50 | ChEMBL;BindingDB |