Molecule Details
InChIKeyLOONVQWRKJLEEG-IYBDPMFKSA-N
Compound NameCID 134524157
Canonical SMILESCOc1cc2c(=O)c3c4ccc(C#N)cc4[nH]c3n(C(C)C)c2c(F)c1N1C[C@@H](C)N(C)[C@@H](C)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.48
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 8.2 IC50 ChEMBL;BindingDB
P29376 LTK Homo sapiens Human PF12810 PF07714 8.2 IC50 ChEMBL;BindingDB
Q12866 MERTK Homo sapiens Human PF00041 PF00047 PF13927 PF07714 8.0 IC50 ChEMBL;BindingDB
Q9UIK4 DAPK2 Homo sapiens Human PF00069 7.7 IC50 ChEMBL;BindingDB
P53355 DAPK1 Homo sapiens Human PF00023 PF12796 PF13637 PF00531 PF00069 7.6 IC50 ChEMBL;BindingDB
P49759 CLK1 Homo sapiens Human PF00069 7.5 IC50 ChEMBL;BindingDB
O43293 DAPK3 Homo sapiens Human PF00069 6.6 IC50 ChEMBL;BindingDB
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 6.0 IC50 ChEMBL;BindingDB