4-(4-(2-Aminopropan-2-yl)phenyl)-2-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenylamino)pyrimidine-5-carbonitrile

InChIKey	`LNPGEMWHMALOTH-UHFFFAOYSA-N`
Compound Name	4-(4-(2-Aminopropan-2-yl)phenyl)-2-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenylamino)pyrimidine-5-carbonitrile
Canonical SMILES	`CN1CCN(CCc2ccc(Nc3ncc(C#N)c(-c4ccc(C(C)(C)N)cc4)n3)cc2)CC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	7.68
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P06493	CDK1	Homo sapiens	Human	PF00069	7.7	pIC50	TTD_MultiTarget
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	7.7	IC50	ChEMBL;BindingDB