Molecule Details
InChIKeyLNIDFQVRZCDVBI-UHFFFAOYSA-N
Compound Name1-(Pyrazin-2-yl)-3-(quinolin-4-yl)urea
Canonical SMILESO=C(Nc1cnccn1)Nc1ccnc2ccccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.61
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 8.1 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.4 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.6 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.3 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.3 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.2 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.0 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 6.0 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.0 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL