Molecule Details
InChIKeyLMXYVLFTZRPNRV-UHFFFAOYSA-N
Compound NameGW305074X
Canonical SMILESO=C1Nc2ccc(I)cc2C1=Cc1cc(Br)c(O)c(Br)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.51
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 8.6 IC50 ChEMBL;BindingDB
P04049 RAF1 Homo sapiens Human PF00130 PF07714 PF02196 8.1 IC50 ChEMBL;BindingDB
P15056 BRAF Homo sapiens Human PF00130 PF07714 PF02196 8.1 IC50 ChEMBL;BindingDB
P10398 ARAF Homo sapiens Human PF00130 PF07714 PF02196 7.8 IC50 ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 7.0 IC50 ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.5 IC50 ChEMBL