Molecule Details
InChIKeyLMXYVLFTZRPNRV-KMKOMSMNSA-N
Compound NameGW-5074
Canonical SMILESO=C1Nc2ccc(I)cc2/C1=C/c1cc(Br)c(O)c(Br)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.29
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P04049 RAF1 Homo sapiens Human PF00130 PF07714 PF02196 8.1 IC50 ChEMBL;BindingDB
P15056 BRAF Homo sapiens Human PF00130 PF07714 PF02196 7.9 IC50 BindingDB
P10398 ARAF Homo sapiens Human PF00130 PF07714 PF02196 7.8 IC50 BindingDB
P42858 HTT Homo sapiens Human PF20925 PF20927 PF12372 PF20926 7.0 Kd ChEMBL;BindingDB
Q9GZQ8 MAP1LC3B Homo sapiens Human PF02991 7.0 Kd ChEMBL;BindingDB
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.6 IC50 ChEMBL;BindingDB
P68400 CSNK2A1 Homo sapiens Human PF00069 6.5 IC50 BindingDB