3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine

InChIKey	`LMVAHLFZGWUGNF-UHFFFAOYSA-N`
Compound Name	3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
Canonical SMILES	`CC(C)n1nc(-c2ccc3c(c2)OCCO3)c2c(N)ncnc21`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	8
Pfam Stratification	Cross-Family
Avg pChEMBL	6.29
Source	BindingDB;ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P42345	MTOR	Homo sapiens	Human	PF02259 PF02260 PF08771 PF23593 PF11865 PF00454	6.3	pIC50	TTD_MultiTarget
P78527	PRKDC	Homo sapiens	Human	PF20500 PF20502 PF08163 PF19704 PF02259 PF02260 PF00454	6.3	IC50	ChEMBL
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.2	pIC50	TTD_MultiTarget
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.0	IC50	ChEMBL
P08631	HCK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.0	IC50	ChEMBL
Q8MMZ7	PKG	Toxoplasma gondii	Pathogen	PF00027 PF00069	6.7	IC50	BindingDB
Q9BJF5	CDPK1	Toxoplasma gondii	Pathogen	PF13499 PF00069	6.7	IC50	ChEMBL;BindingDB
A3FQ16		Cryptosporidium parvum (strain Iowa II)	Pathogen	PF13499 PF00069	6.0	IC50	BindingDB