Molecule Details
InChIKeyLMLIBNUOIWAJFC-UHFFFAOYSA-N
Compound NameN-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide
Canonical SMILESCCS(=O)(=O)Nc1cc(-c2cn(C)c3c(=O)[nH]ccc23)cc2c1ccn2C(C)(c1ccccn1)c1ccccn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Homologous
Avg pChEMBL8.19
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q58F21 BRDT Homo sapiens Human PF17035 PF17105 PF00439 9.6 Kd ChEMBL
Q15059 BRD3 Homo sapiens Human PF17035 PF00439 9.5 Kd ChEMBL
P25440 BRD2 Homo sapiens Human PF17035 PF00439 9.2 Kd ChEMBL
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 9.1 IC50 ChEMBL;BindingDB
P21675 TAF1 Homo sapiens Human PF00439 PF12157 PF09247 PF15288 8.0 Kd ChEMBL;BindingDB
Q09472 EP300 Homo sapiens Human PF00439 PF09030 PF08214 PF02172 PF23570 PF06001 PF02135 PF00569 7.4 Kd ChEMBL;BindingDB
Q8IZX4 TAF1L Homo sapiens Human PF00439 PF12157 PF09247 PF15288 7.4 Kd ChEMBL
Q92793 CREBBP Homo sapiens Human PF00439 PF09030 PF08214 PF02172 PF23570 PF06001 PF02135 PF00569 7.0 Kd ChEMBL
P55201 BRPF1 Homo sapiens Human PF00439 PF10513 PF13831 PF00855 PF13832 6.4 Kd ChEMBL