Molecule Details
InChIKeyLMGQGPVCSYOMNS-UHFFFAOYSA-N
Compound Name2-(2-hydroxy-(1,1'-biphenyl)-3-yl)-1H-1,3-benzodiazole-5-carboximidamide
Canonical SMILESN=C(N)c1ccc2nc(-c3cccc(-c4ccccc4)c3O)[nH]c2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL6.31
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB01725
Drug Name2-{2-hydroxy-[1,1'-biphenyl]-3-yl}-1H-1,3-benzodiazole-5-carboximidamide
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 14325 CHEMBL327715 ChemSpider: 11452336 PDB: 130 PubChem:5353305 PubChem:46507079 ZINC: ZINC000002047577
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P00740 F9 Homo sapiens Human PF00008 PF14670 PF00594 PF00089 7.0 Ki ChEMBL;BindingDB
P00749 PLAU Homo sapiens Human PF00051 PF00089 6.4 Ki ChEMBL;BindingDB
P00734 F2 Homo sapiens Human PF00594 PF00051 PF09396 PF00089 6.3 Ki BindingDB
P00750 PLAT Homo sapiens Human PF00008 PF00039 PF00051 PF00089 6.1 Ki ChEMBL;BindingDB
P00742 F10 Homo sapiens Human PF00008 PF14670 PF00594 PF00089 6.0 Ki BindingDB
P00747 PLG Homo sapiens Human PF00051 PF00024 PF00089 6.0 Ki BindingDB
DrugBank Target Actions (3)
Target Gene Target Name Action Type
P00734 F2 Prothrombin binder targets
P00749 PLAU Urokinase-type plasminogen activator binder targets
P07477 PRSS1 Serine protease 1 binder targets