Molecule Details
InChIKeyLMBWSYZSUOEYSN-UHFFFAOYSA-N
Compound NameDiethyldithiocarbamic Acid
Canonical SMILESCCN(CC)C(=S)S
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL6.24
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB02520
Drug NameDitiocarb
CAS Number147-84-2
Groups investigational
ATC Codes nan
DescriptionA chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.

Categories: Acids, Acyclic Adjuvants, Immunologic Anti-Infective Agents Carbamates Chelating Agents Compounds used in a research, industrial, or household setting Cytochrome P-450 CYP2E1 Inhibitors Cytochrome P-450 CYP2E1 Inhibitors (strength unknown) Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strong) Cytochrome P-450 CYP3A5 Inhibitors Cytochrome P-450 CYP3A5 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inhibitors Immunologic Factors Sequestering Agents Sulfur Compounds Thiocarbamates
Cross-references: BindingDB: 50428474 ChEBI: 144353 CHEMBL961 ChemSpider: 8639 C19150 PDB: DCD PubChem:8987 PubChem:46504708 RxCUI: 1427193 ZINC: ZINC000003633221
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P57764 GSDMD Homo sapiens Human PF04598 PF17708 6.4 IC50 ChEMBL
P05181 CYP2E1 Homo sapiens Human PF00067 6.1 IC50 ChEMBL
DrugBank Target Actions (3)
Target Gene Target Name Action Type
P05181 CYP2E1 Cytochrome P450 2E1 inhibitor enzymes
P08684 CYP3A4 Cytochrome P450 3A4 inhibitor enzymes
P20815 CYP3A5 Cytochrome P450 3A5 inhibitor enzymes