Molecule Details
InChIKeyLLCRBOWRJOUJAE-UHFFFAOYSA-N
Compound NameBalicatib
Canonical SMILESCCCN1CCN(c2ccc(C(=O)NC3(C(=O)NCC#N)CCCCC3)cc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL7.81
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12239
Drug NameBalicatib
CAS Number354813-19-7
Groups investigational
ATC Codes nan
DescriptionBalicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.

Categories: Acids, Carbocyclic Amides Benzene Derivatives Benzoates
Cross-references: BindingDB: 19855 CHEMBL371064 ChemSpider: 8377195 PubChem:10201696 PubChem:347828518 ZINC: ZINC000003954923
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P07339 CTSD Homo sapiens Human PF07966 PF00026 8.9 Ki ChEMBL;BindingDB
P43235 CTSK Homo sapiens Human PF08246 PF00112 8.8 IC50 ChEMBL;BindingDB
P07858 CTSB Homo sapiens Human PF00112 PF08127 7.2 IC50 ChEMBL;BindingDB
P07711 CTSL Homo sapiens Human PF08246 PF00112 6.3 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P43235 CTSK Cathepsin K inhibitor targets