Molecule Details
InChIKeyLKHMVKNMSWRHJH-GOSISDBHSA-N
Compound NameAtr-IN-20
Canonical SMILESC[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1cccc(S(C)(=O)=O)c1)C2(C)C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.64
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13535 ATR Homo sapiens Human PF02259 PF02260 PF23593 PF25030 PF25032 PF00454 PF08064 8.5 IC50 ChEMBL
P42345 MTOR Homo sapiens Human PF02259 PF02260 PF08771 PF23593 PF11865 PF00454 7.8 IC50 ChEMBL
P78527 PRKDC Homo sapiens Human PF20500 PF20502 PF08163 PF19704 PF02259 PF02260 PF00454 6.2 IC50 ChEMBL
P08684 CYP3A4 Homo sapiens Human PF00067 6.0 IC50 ChEMBL
P33261 CYP2C19 Homo sapiens Human PF00067 6.0 IC50 ChEMBL
P42336 PIK3CA Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 6.0 IC50 ChEMBL
Q13315 ATM Homo sapiens Human PF02259 PF02260 PF00454 PF11640 6.0 IC50 ChEMBL