Molecule Details
InChIKeyLKEGXJXRNBALBV-PMCHYTPCSA-N
Compound NamedBET1
Canonical SMILESCc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCNC(=O)COc1cccc3c1C(=O)N(C1CCC(=O)NC1=O)C3=O)c1nnc(C)n1-2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL8.07
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
Q58F21 BRDT Homo sapiens Human PF17035 PF17105 PF00439 8.2 Kd ChEMBL;BindingDB
Q15059 BRD3 Homo sapiens Human PF17035 PF00439 8.2 Ki ChEMBL
Q16531 DDB1 Homo sapiens Human PF10433 PF23726 PF03178 8.1 IC50 ChEMBL;BindingDB
Q96SW2 CRBN Homo sapiens Human PF02190 PF03226 8.1 IC50 ChEMBL
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 7.7 IC50 ChEMBL