Molecule Details
| InChIKey | LIFDPEORUVTOCP-UHFFFAOYSA-N |
|---|---|
| Compound Name | Saripidem |
| Canonical SMILES | CCCC(=O)N(C)Cc1c(-c2ccc(Cl)cc2)nc2ccccn12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.46 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB19528 |
|---|---|
| Drug Name | Saripidem |
| CAS Number | 103844-86-6 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Saripidem is a small molecule drug. Saripidem has a monoisotopic molecular weight of 341.13 Da. |
Cross-references: BindingDB: 50290077 CHEMBL73416
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P14867 | GABRA1 | Homo sapiens | Human | PF02931 PF02932 | 9.0 | IC50 | ChEMBL;BindingDB |
| P31644 | GABRA5 | Homo sapiens | Human | PF02931 PF02932 | 8.5 | IC50 | ChEMBL;BindingDB |
| P18507 | GABRG2 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | IC50 | ChEMBL |
| P47870 | GABRB2 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | IC50 | ChEMBL |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| Q99928 | GABRG3 | Gamma-aminobutyric acid receptor subunit gamma-3 | modulator | targets |