Molecule Details
InChIKeyLIEUQFMVFKJKHX-UHFFFAOYSA-N
Compound NameErk5-IN-4
Canonical SMILESCn1cc(NC(=O)c2cc(C(=O)c3c(Cl)ccc(Cl)c3F)c[nH]2)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL7.38
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 8.9 Kd ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 8.9 Kd ChEMBL
Q13163 MAP2K5 Homo sapiens Human PF00564 PF00069 8.6 Kd ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 7.3 Kd ChEMBL
O15075 DCLK1 Homo sapiens Human PF03607 PF00069 7.2 Kd ChEMBL
Q13164 MAPK7 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.7 Kd ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.5 Kd ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.4 Kd ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.4 Kd ChEMBL