InChIKey	LHHCSNFAOIFYRV-DOVBMPENSA-N
Compound Name	Boceprevir
Canonical SMILES	CC(C)(C)NC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(C)C)C(C)(C)C
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	8
Pfam Stratification	Cross-Family
Avg pChEMBL	7.37
Source	ChEMBL;BindingDB

DrugBank ID	DB08873
Drug Name	Boceprevir
CAS Number	394730-60-0
Groups	approved withdrawn
ATC Codes	J05AP03
Description	Boceprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 bein...

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Categories: Amino Acids Amino Acids, Cyclic Amino Acids, Peptides, and Proteins Antiinfectives for Systemic Use Antiviral Agents Antivirals for Systemic Use Antivirals for treatment of HCV infections Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strong) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Inhibitors Cytochrome P-450 CYP3A5 Inhibitors (strong) Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Direct Acting Antivirals Enzyme Inhibitors HCV NS3/4A Protease Inhibitors Imino Acids NS3/4A Protease Inhibitors P-glycoprotein inhibitors Protease Inhibitors

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Cross-references: BindingDB: 12311 ChEBI: 68621 CHEMBL218394 ChemSpider: 8499830 Drugs Product Database (DPD): 20878 D08876 PDB: HU5 PharmGKB: PA165948902 PubChem:10324367 PubChem:175427127 RxCUI: 1102129 Wikipedia: Boceprevir