Molecule Details
| InChIKey | LHAZDFBNDIQNSG-VCHYOVAHSA-N |
|---|---|
| Compound Name | 2-(3-methoxyanilino)-N-[(E)-pyridin-4-ylmethylideneamino]acetamide |
| Canonical SMILES | COc1cccc(NCC(=O)N/N=C/c2ccncc2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.13 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35626 | GRK3 | Homo sapiens | Human | PF00169 PF00069 PF00615 | 8.0 | Ki | ChEMBL |
| P25098 | GRK2 | Homo sapiens | Human | PF00169 PF00069 PF00615 | 7.3 | IC50 | ChEMBL;BindingDB |
| O75116 | ROCK2 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 7.2 | IC50 | ChEMBL;BindingDB |
| P34947 | GRK5 | Homo sapiens | Human | PF00069 PF00615 | 6.0 | Ki | ChEMBL |