N-[[4-[[5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-yl]amino]phenyl]methyl]-N'-hydroxypropanediamide

InChIKey	`LFWRZTGKNXDMJU-UHFFFAOYSA-N`
Compound Name	N-[[4-[[5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-yl]amino]phenyl]methyl]-N'-hydroxypropanediamide
Canonical SMILES	`Cc1nc2c(F)cc(-c3nc(Nc4ccc(CNC(=O)CC(=O)NO)cc4)ncc3F)cc2n1C(C)C`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	7.82
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P11802	CDK4	Homo sapiens	Human	PF00069	8.9	IC50	ChEMBL
Q9UBN7	HDAC6	Homo sapiens	Human	PF00850 PF02148	8.2	IC50	ChEMBL
Q13547	HDAC1	Homo sapiens	Human	PF00850	7.6	IC50	ChEMBL
O15379	HDAC3	Homo sapiens	Human	PF00850	7.2	IC50	ChEMBL
Q969S8	HDAC10	Homo sapiens	Human	PF00850	7.1	IC50	ChEMBL