Molecule Details
| InChIKey | LFAHWMOZPVCJAY-HNNXBMFYSA-N |
|---|---|
| Compound Name | 5-[(5S)-5-(4-chlorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl]-3-methyl-2H-pyrazolo[3,4-b]pyridine |
| Canonical SMILES | Cc1n[nH]c2ncc(-c3nnc4n3[C@H](c3ccc(Cl)cc3)CC4)cc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 8 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.59 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (8)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P24863 | CCNC | Homo sapiens | Human | PF16899 PF00134 | 8.8 | IC50 | ChEMBL |
| P49336 | CDK8 | Homo sapiens | Human | PF00069 | 8.8 | IC50 | ChEMBL |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 8.4 | Kd | ChEMBL |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 8.2 | Kd | ChEMBL |
| P49760 | CLK2 | Homo sapiens | Human | PF00069 | 7.1 | Kd | ChEMBL |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 7.1 | Kd | ChEMBL |
| Q9Y6M4 | CSNK1G3 | Homo sapiens | Human | PF12605 PF00069 | 6.2 | Kd | ChEMBL |
| Q9NRM7 | LATS2 | Homo sapiens | Human | PF00069 PF00433 | 6.1 | Kd | ChEMBL |