N-(2-Methoxyethyl)-4-((4-(2-methyl-1-(1-methylethyl)-1H-imidazol-5-YL)pyrimidin-2-YL)amino)benzenesulfonamide — MultiTargetDB

Molecule Details

InChIKey	`LDXLQEXLXZCYSR-UHFFFAOYSA-N`
Compound Name	N-(2-Methoxyethyl)-4-((4-(2-methyl-1-(1-methylethyl)-1H-imidazol-5-YL)pyrimidin-2-YL)amino)benzenesulfonamide
Canonical SMILES	`COCCNS(=O)(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C(C)C)n2)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	9.0
Source	TTD_MultiTarget

2D Structure

2D structure

Activity Profile

DrugBank Annotations

DrugBank ID	DB07790
Drug Name	N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE
CAS Number	nan
Groups	experimental
ATC Codes	nan
Description	nan

Cross-references: BindingDB: 50263028 CHEMBL478409 ChemSpider: 24698537 PDB: FRT PubChem:24963033 PubChem:99444261 ZINC: ZINC000038995985

Target Activities (2)

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P11802	CDK4	Homo sapiens	Human	PF00069	9.0	pIC50	TTD_MultiTarget
P24941	CDK2	Homo sapiens	Human	PF00069	9.0	pIC50	TTD_MultiTarget

DrugBank Target Actions (1)

Target	Gene	Target Name	Action	Type
P24941	CDK2	Cyclin-dependent kinase 2	binder	targets