Molecule Details
InChIKeyLDHYCINFJPCBRY-UHFFFAOYSA-N
Compound Name5-(3-Methoxyprop-1-ynyl)-3-thiophen-2-yl-2,4-dihydroindeno[1,2-c]pyrazole
Canonical SMILESCOCC#Cc1cccc2c1Cc1c(-c3cccs3)n[nH]c1-2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.2
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.9 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.2 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.0 Ki ChEMBL
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 6.0 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.0 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL