Molecule Details
| InChIKey | LDCYZAJDBXYCGN-VIFPVBQESA-N |
|---|---|
| Compound Name | Oxitriptan |
| Canonical SMILES | N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.79 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB02959 |
|---|---|
| Drug Name | Oxitriptan |
| CAS Number | 4350-09-8 |
| Groups | approved investigational nutraceutical withdrawn |
| ATC Codes | N06AX01 |
| Description | 5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in the United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant... |
Categories: Amino Acids Amino Acids, Aromatic Amino Acids, Cyclic Amino Acids, Peptides, and Proteins Antidepressive Agents Antidepressive Agents, Second-Generation Central Nervous System Agents Central Nervous System Depressants Nervous System Psychoanaleptics Psychotropic Drugs
Cross-references: BindingDB: 50403163 ChEBI: 58266 CHEMBL350221 ChemSpider: 388413 C00643 D07339 PDB: 4PQ PubChem:439280 PubChem:46505826 RxCUI: 94 Wikipedia: 5-Hydroxytryptophan ZINC: ZINC000000895330
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| Q9RVD6 | Q9RVD6 | Tryptophan--tRNA ligase 2 | binder | targets |