LDAVCWRDFVEWLN-QHCPKHFHSA-N

InChIKey	`LDAVCWRDFVEWLN-QHCPKHFHSA-N`
Canonical SMILES	`Cc1ccc2cc(Nc3nn([C@]4(CC#N)CCCOC4)c4cc[nH]c(=O)c34)ccc2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	9.25
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P23458	JAK1	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	10.0	IC50	ChEMBL;BindingDB
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	8.5	IC50	ChEMBL;BindingDB