4-(4-chlorophenyl)-5-(1,5-dimethyl-6-oxo-3-pyridinyl)-3-methyl-1-(2-methylpyrazol-3-yl)-4H-pyrrolo[3,4-d]pyrazol-6-one

InChIKey	`LCXHXIMNUYTCEI-UHFFFAOYSA-N`
Compound Name	4-(4-chlorophenyl)-5-(1,5-dimethyl-6-oxo-3-pyridinyl)-3-methyl-1-(2-methylpyrazol-3-yl)-4H-pyrrolo[3,4-d]pyrazol-6-one
Canonical SMILES	`Cc1nn(-c2ccnn2C)c2c1C(c1ccc(Cl)cc1)N(c1cc(C)c(=O)n(C)c1)C2=O`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.12
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O60885	BRD4	Homo sapiens	Human	PF17035 PF17105 PF00439	7.2	IC50	ChEMBL;BindingDB
P25440	BRD2	Homo sapiens	Human	PF17035 PF00439	7.2	IC50	ChEMBL;BindingDB
Q15059	BRD3	Homo sapiens	Human	PF17035 PF00439	7.0	IC50	ChEMBL;BindingDB