Molecule Details
| InChIKey | LCVIRAZGMYMNNT-UHFFFAOYSA-N |
|---|---|
| Compound Name | MK-5108 |
| Canonical SMILES | O=C(O)C1(Cc2cccc(Nc3nccs3)n2)CCC(Oc2cccc(Cl)c2F)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.26 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O14965 | AURKA | Homo sapiens | Human | PF00069 | 10.2 | IC50 | BindingDB |
| Q96GD4 | AURKB | Homo sapiens | Human | PF00069 | 8.3 | IC50 | BindingDB |
| Q9UQB9 | AURKC | Homo sapiens | Human | PF00069 | 7.9 | IC50 | BindingDB |
| P29317 | EPHA2 | Homo sapiens | Human | PF14575 PF25599 PF01404 PF00041 PF07714 PF00536 | 6.6 | Kd | BindingDB |