Molecule Details
InChIKeyLCKDESRGCHSHHO-UHFFFAOYSA-N
Compound Name3-[(4-Chlorophenyl)methylamino]-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione
Canonical SMILESO=c1c(NCc2ccc(Cl)cc2)c(Nc2ccncc2)c1=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)18
Pfam Stratification Homologous
Avg pChEMBL6.48
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (18)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 7.5 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 7.1 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.0 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.8 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.5 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.5 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.5 Ki ChEMBL
O14757 CHEK1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.3 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.3 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.3 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.3 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.2 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.0 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 6.0 Ki ChEMBL