8-(2-methoxyethyl)-2-[2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridinyl]-5,7-dihydropyrazino[2,3-b]pyrazin-6-one

InChIKey	`LBQBMEVXMVNFHK-UHFFFAOYSA-N`
Compound Name	8-(2-methoxyethyl)-2-[2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridinyl]-5,7-dihydropyrazino[2,3-b]pyrazin-6-one
Canonical SMILES	`COCCN1CC(=O)Nc2ncc(-c3ccc(-c4nc[nH]n4)nc3C)nc21`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.18
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P42345	MTOR	Homo sapiens	Human	PF02259 PF02260 PF08771 PF23593 PF11865 PF00454	7.2	IC50	ChEMBL;BindingDB
Q8N122	RPTOR	Homo sapiens	Human	PF02985 PF14538 PF00400	7.2	IC50	ChEMBL
Q9BVC4	MLST8	Homo sapiens	Human	PF00400	7.2	IC50	ChEMBL