N-(2-methyl-4-(5-(2-(4-(4-(pyrrolidin-1-yl)piperidine-1-carbonyl)phenylamino)pyrimidin-4-yl)thiophen-2-yl)butan-2-yl)acetamide

InChIKey	`LBJKDVWECYXKJZ-UHFFFAOYSA-N`
Compound Name	N-(2-methyl-4-(5-(2-(4-(4-(pyrrolidin-1-yl)piperidine-1-carbonyl)phenylamino)pyrimidin-4-yl)thiophen-2-yl)butan-2-yl)acetamide
Canonical SMILES	`CC(=O)NC(C)(C)CCc1ccc(-c2ccnc(Nc3ccc(C(=O)N4CCC(N5CCCC5)CC4)cc3)n2)s1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.22
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14920	IKBKB	Homo sapiens	Human	PF18397 PF12179 PF00069	6.5	IC50	ChEMBL;BindingDB
O15111	CHUK	Homo sapiens	Human	PF18397 PF12179 PF00069	6.1	IC50	ChEMBL
Q9Y6K9	IKBKG	Homo sapiens	Human	PF16516 PF11577 PF18414	6.1	IC50	ChEMBL