Molecule Details
InChIKeyLAYMXNJSUDFINH-UHFFFAOYSA-N
Compound Name8-[3-Chloro-5-[4-[1-(2-hydroxy-2-methylpropyl)pyrazol-4-yl]phenyl]-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one
Canonical SMILESCC(C)(O)Cn1cc(-c2ccc(-c3cncc(Cl)c3N3CCC4(CCNC4=O)CC3)cc2)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.67
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P24863 CCNC Homo sapiens Human PF16899 PF00134 8.8 IC50 ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 8.8 IC50 ChEMBL;BindingDB
Q9BWU1 CDK19 Homo sapiens Human PF00069 8.4 IC50 ChEMBL