(2R,4R)-4-amino-8-[6-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]pyrido[2,3-b]pyrazin-2-yl]-8-azaspiro[4.5]decan-2-ol

InChIKey	`LANVDWAEBRQKDI-SWLSCSKDSA-N`
Compound Name	(2R,4R)-4-amino-8-[6-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]pyrido[2,3-b]pyrazin-2-yl]-8-azaspiro[4.5]decan-2-ol
Canonical SMILES	`Nc1nccc(Sc2ccc3nc(N4CCC5(CC4)C[C@@H](O)C[C@H]5N)cnc3n2)c1Cl`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.97
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q06124	PTPN11	Homo sapiens	Human	PF00017 PF00102	7.2	IC50	ChEMBL
P27361	MAPK3	Homo sapiens	Human	PF00069	6.8	IC50	ChEMBL
P28482	MAPK1	Homo sapiens	Human	PF00069	6.8	IC50	ChEMBL