Molecule Details
InChIKeyLAMWYYXJYIQOQL-UHFFFAOYSA-N
Compound NameIndolocarbazole deriv. 4(b)
Canonical SMILESO=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3cccc(Br)c3c21
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.89
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13554 CAMK2B Homo sapiens Human PF08332 PF00069 7.2 IC50 ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 7.2 IC50 ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 7.2 IC50 ChEMBL
Q9UQM7 CAMK2A Homo sapiens Human PF08332 PF00069 7.2 IC50 ChEMBL
P11802 CDK4 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
P24385 CCND1 Homo sapiens Human PF02984 PF00134 7.1 IC50 ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.0 IC50 ChEMBL
P22612 PRKACG Homo sapiens Human PF00069 7.0 IC50 ChEMBL
P22694 PRKACB Homo sapiens Human PF00069 7.0 IC50 ChEMBL
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 6.7 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.7 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.7 pIC50 TTD_MultiTarget
P06493 CDK1 Homo sapiens Human PF00069 6.6 pIC50 TTD_MultiTarget
O95067 CCNB2 Homo sapiens Human PF02984 PF00134 6.5 IC50 ChEMBL
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.5 IC50 ChEMBL
Q8WWL7 CCNB3 Homo sapiens Human PF02984 PF00134 6.5 IC50 ChEMBL