Molecule Details
InChIKeyKZVXSSLUUGFVFR-UHFFFAOYSA-N
Compound NameD4R agonist-1
Canonical SMILESc1ccc(N2CCN(CCCc3nc4ccccc4s3)CC2)nc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL6.88
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
P08908 HTR1A Homo sapiens Human PF00001 8.2 Ki ChEMBL
P21917 DRD4 Homo sapiens Human PF00001 8.0 Ki ChEMBL;BindingDB
P28223 HTR2A Homo sapiens Human PF00001 7.3 Ki ChEMBL
P18825 ADRA2C Homo sapiens Human PF00001 7.1 Ki ChEMBL
Q5BJF2 TMEM97 Homo sapiens Human PF05241 7.1 Ki ChEMBL
P41595 HTR2B Homo sapiens Human PF00001 7.1 IC50 ChEMBL
P34969 HTR7 Homo sapiens Human PF00001 7.0 Ki ChEMBL
P08913 ADRA2A Homo sapiens Human PF00001 6.5 Ki ChEMBL
P18089 ADRA2B Homo sapiens Human PF00001 6.5 Ki ChEMBL
P35368 ADRA1B Homo sapiens Human PF00001 6.4 Ki ChEMBL
P35367 HRH1 Homo sapiens Human PF00001 6.4 Ki ChEMBL
P35348 ADRA1A Homo sapiens Human PF00001 6.2 Ki ChEMBL
P35462 DRD3 Homo sapiens Human PF00001 6.2 Ki ChEMBL
P23975 SLC6A2 Homo sapiens Human PF00209 6.2 Ki ChEMBL