Molecule Details
InChIKeyKZSUQTFUAGZIRM-UHFFFAOYSA-N
Compound NameN-[3-[[4-[1-tert-butyl-3-(3-hydroxyphenyl)pyrazol-4-yl]-2-pyridinyl]amino]propyl]-4-methoxybenzenesulfonamide
Canonical SMILESCOc1ccc(S(=O)(=O)NCCCNc2cc(-c3cn(C(C)(C)C)nc3-c3cccc(O)c3)ccn2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL7.72
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P45983 MAPK8 Homo sapiens Human PF00069 8.7 IC50 ChEMBL
P53779 MAPK10 Homo sapiens Human PF00069 8.0 IC50 ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 7.9 IC50 ChEMBL
P10635 CYP2D6 Homo sapiens Human PF00067 7.6 IC50 ChEMBL
P08684 CYP3A4 Homo sapiens Human PF00067 6.4 IC50 ChEMBL