Molecule Details
InChIKeyKZRDVFBPXXGSPD-UHFFFAOYSA-N
Compound Name1-[4-[4-Amino-1-[2-[4-(dimethylamino)piperidin-1-yl]ethyl]pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-3-tert-butylurea
Canonical SMILESCOc1cc(-c2nn(CCN3CCC(N(C)C)CC3)c3ncnc(N)c23)ccc1NC(=O)NC(C)(C)C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Homologous
Avg pChEMBL6.62
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL;BindingDB
P07947 YES1 Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL;BindingDB
P09769 FGR Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.5 IC50 ChEMBL;BindingDB
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
Q13882 PTK6 Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB