Molecule Details
| InChIKey | KYRSNWPSSXSNEP-ZRTHHSRSSA-N |
|---|---|
| Compound Name | Mozenavir |
| Canonical SMILES | Nc1cccc(CN2C(=O)N(Cc3cccc(N)c3)[C@H](Cc3ccccc3)[C@H](O)[C@@H](O)[C@H]2Cc2ccccc2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.54 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB02102 |
|---|---|
| Drug Name | Mozenavir |
| CAS Number | 174391-92-5 |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Categories: Amides
Cross-references: BindingDB: 151 CHEMBL223824 ChemSpider: 135759 PDB: DMQ PubChem:154044 PubChem:46504938 Wikipedia: Mozenavir ZINC: ZINC000003831996
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P04585 | gag-pol | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) | Pathogen | PF00540 PF19317 PF00552 PF02022 PF00075 PF00665 PF00077 PF00078 PF06815 PF06817 PF00098 | 9.6 | Ki | BindingDB |
| Q72874 | pol | Human immunodeficiency virus type 1 | Pathogen | PF00077 | 9.6 | Ki | ChEMBL |
| Q9YQ12 | protease | Human immunodeficiency virus type 1 | Pathogen | PF00077 | 9.5 | Ki | ChEMBL;BindingDB |