Molecule Details
| InChIKey | KYASUVSAKOTGNF-UHFFFAOYSA-N |
|---|---|
| Compound Name | US10307425, Example 4 |
| Canonical SMILES | CN1CCC(Cn2nc(-c3ccc4cc(OC5CC5)ccc4c3)c3c(N)ncnc32)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.02 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q12809 | KCNH2 | Homo sapiens | Human | PF00027 PF00520 PF13426 | 6.4 | IC50 | ChEMBL;BindingDB |
| A0A0F7UUA6 | Toxoplasma gondii (strain ATCC 50861 / VEG) | Pathogen | PF13499 PF00069 | 8.8 | IC50 | BindingDB | |
| Q9BJF5 | CDPK1 | Toxoplasma gondii | Pathogen | PF13499 PF00069 | 8.8 | IC50 | ChEMBL;BindingDB |