Molecule Details
InChIKeyKYACBMRLQMEIAI-UHFFFAOYSA-N
Compound Name3-(4-(4-iodophenoxy)thieno[2,3-c]pyridin-2-yl)-1,2,4-oxadiazol-5(2H)-one
Canonical SMILESO=c1nc(-c2cc3c(Oc4ccc(I)cc4)cncc3s2)[nH]o1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)30
Pfam Stratification Cross-Family
Avg pChEMBL6.58
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (30)
Target Gene Organism Category Pfam pChEMBL Type Source
Q8NE63 HIPK4 Homo sapiens Human PF00069 7.9 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.6 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.5 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 7.4 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 7.3 IC50 ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 7.0 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.8 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q9NYL2 MAP3K20 Homo sapiens Human PF07714 PF07647 6.5 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.4 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.4 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.4 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.3 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 6.3 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.1 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.1 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.1 Ki ChEMBL
Q96RG2 PASK Homo sapiens Human PF13426 PF00069 6.1 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.1 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.0 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL