Molecule Details
InChIKeyKXPWWMPXNUOYOH-UHFFFAOYSA-N
Compound Name6-(3-Aminopropoxy)-4-[4-[(6-chloro-1,3-benzoxazol-2-yl)amino]phenyl]-2,3-dihydroisoindol-1-one
Canonical SMILESNCCCOc1cc2c(c(-c3ccc(Nc4nc5ccc(Cl)cc5o4)cc3)c1)CNC2=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)24
Pfam Stratification Cross-Family
Avg pChEMBL6.59
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (24)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 7.4 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.3 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.2 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 7.1 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 7.0 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 7.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 7.0 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.8 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.8 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.5 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.5 Ki ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.4 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.4 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P31751 AKT2 Homo sapiens Human PF00169 PF00069 PF00433 6.3 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.3 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P05129 PRKCG Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.1 Ki ChEMBL
P15735 PHKG2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.0 Ki ChEMBL