Molecule Details
| InChIKey | KXHWJJLARFHTQI-UHFFFAOYSA-N |
|---|---|
| Compound Name | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 12 |
| Canonical SMILES | CCCSc1c(F)c(F)c(S(N)(=O)=O)c(NC2CCCCCCC2)c1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.9 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 7.6 | Kd | ChEMBL;BindingDB |
| Q8N1Q1 | CA13 | Homo sapiens | Human | PF00194 | 7.5 | Kd | ChEMBL;BindingDB |
| P43166 | CA7 | Homo sapiens | Human | PF00194 | 6.7 | Kd | ChEMBL;BindingDB |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 6.4 | Kd | ChEMBL;BindingDB |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 6.3 | Kd | ChEMBL;BindingDB |