N(1)Gly-Arg-Cys(2)-Thr-Arg-Ser-Ile-Pro-Pro-Ile-Cys(2)-Phe-Pro-Asp(1)-OH

InChIKey	`KWSMBEJYQLCPRA-MFPJKNJCSA-N`
Compound Name	N(1)Gly-Arg-Cys(2)-Thr-Arg-Ser-Ile-Pro-Pro-Ile-Cys(2)-Phe-Pro-Asp(1)-OH
Canonical SMILES	`CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)CC(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	6
Pfam Stratification	Homologous
Avg pChEMBL	8.53
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P07477	PRSS1	Homo sapiens	Human	PF00089	10.5	Ki	ChEMBL;BindingDB
P07478	PRSS2	Homo sapiens	Human	PF00089	10.5	Ki	ChEMBL
P35030	PRSS3	Homo sapiens	Human	PF00089	10.5	Ki	ChEMBL
P00747	PLG	Homo sapiens	Human	PF00051 PF00024 PF00089	6.9	Ki	ChEMBL;BindingDB
P00734	F2	Homo sapiens	Human	PF00594 PF00051 PF09396 PF00089	6.4	Ki	ChEMBL;BindingDB
Q8IU80	TMPRSS6	Homo sapiens	Human	PF00057 PF01390 PF00089	6.3	Ki	ChEMBL;BindingDB