2-[3-[3-(4-Methylpiperazin-1-Yl)propoxy]phenyl]-~{n}-[4-(1~{h}-Pyrrolo[2,3-B]pyridin-3-Yl)-1,3-Thiazol-2-Yl]ethanamide

InChIKey	`KWQRIWDMNAKJAF-UHFFFAOYSA-N`
Compound Name	2-[3-[3-(4-Methylpiperazin-1-Yl)propoxy]phenyl]-~{n}-[4-(1~{h}-Pyrrolo[2,3-B]pyridin-3-Yl)-1,3-Thiazol-2-Yl]ethanamide
Canonical SMILES	`CN1CCN(CCCOc2cccc(CC(=O)Nc3nc(-c4c[nH]c5ncccc45)cs3)c2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.81
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	8.2	Ki	ChEMBL;BindingDB
O14578	CIT	Homo sapiens	Human	PF00780 PF00169 PF00069 PF00433	6.2	Ki	ChEMBL;BindingDB
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	6.0	Ki	ChEMBL;BindingDB