5-(5-amino-2-(2,6-difluorobenzyl)-7-(4-fluorophenyl)-[1,2,4]triazolo[1,5-c]pyrimidin-8-yl)-l-methylpyridin-2(1H)-one

InChIKey	`KVTHXAIJSHWNRJ-UHFFFAOYSA-N`
Compound Name	5-(5-amino-2-(2,6-difluorobenzyl)-7-(4-fluorophenyl)-[1,2,4]triazolo[1,5-c]pyrimidin-8-yl)-l-methylpyridin-2(1H)-one
Canonical SMILES	`Cn1cc(-c2c(-c3ccc(F)cc3)nc(N)n3nc(Cc4c(F)cccc4F)nc23)ccc1=O`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.54
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P30542	ADORA1	Homo sapiens	Human	PF00001	9.7	IC50	ChEMBL;BindingDB
P29274	ADORA2A	Homo sapiens	Human	PF00001	8.7	IC50	ChEMBL;BindingDB
P29275	ADORA2B	Homo sapiens	Human	PF00001	7.2	IC50	ChEMBL;BindingDB