Molecule Details
| InChIKey | KVLSZJPFQDRDPI-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-[4-(4-methylpiperazin-1-yl)phenyl]-3-(1H-pyrrolo[2,3-b]pyridin-4-yl)furo[3,2-b]pyridine |
| Canonical SMILES | CN1CCN(c2ccc(-c3cnc4c(-c5ccnc6[nH]ccc56)coc4c3)cc2)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.56 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O00238 | BMPR1B | Homo sapiens | Human | PF01064 PF07714 PF08515 | 7.8 | IC50 | ChEMBL |
| Q04771 | ACVR1 | Homo sapiens | Human | PF01064 PF07714 PF08515 | 7.8 | IC50 | ChEMBL |
| P37023 | ACVRL1 | Homo sapiens | Human | PF07714 PF08515 | 7.4 | IC50 | ChEMBL |
| P36894 | BMPR1A | Homo sapiens | Human | PF01064 PF07714 PF08515 | 7.2 | IC50 | ChEMBL |