Molecule Details
InChIKeyKVBZUTNKUVNMNN-INIZCTEOSA-N
Compound NameN-{4-[4-(2-Amino-4-Oxo-1,4-Dihydrothieno[2,3-D]pyrimidin-6-Yl)butyl]benzoyl}-L-Glutamic Acid
Canonical SMILESNc1nc2sc(CCCCc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cc2c(=O)[nH]1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.88
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P15328 FOLR1 Homo sapiens Human PF03024 8.1 IC50 ChEMBL;BindingDB
P22102 GART Homo sapiens Human PF00586 PF02769 PF00551 PF01071 PF02843 PF02844 7.9 IC50 ChEMBL;BindingDB
P14207 FOLR2 Homo sapiens Human PF03024 7.7 IC50 ChEMBL;BindingDB