Molecule Details
InChIKeyKUCNBQPAJZRQMJ-UHFFFAOYSA-N
Compound Name1-[2-[4-[(dimethylamino)methyl]piperidin-1-yl]ethyl]-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine
Canonical SMILESCN(C)CC1CCN(CCn2nc(-c3cnc4[nH]ccc4c3)c3c(N)ncnc32)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Homologous
Avg pChEMBL6.81
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
P07947 YES1 Homo sapiens Human PF07714 PF00017 PF00018 7.6 IC50 ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 7.4 IC50 ChEMBL;BindingDB
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL;BindingDB
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL;BindingDB
P09769 FGR Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL;BindingDB
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.6 IC50 ChEMBL;BindingDB
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.4 IC50 ChEMBL;BindingDB
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB