Molecule Details
InChIKeyKTRGYJLQTZDGPX-UHFFFAOYSA-N
Compound Name7,8-Dimethoxypyrrolo[3,4-c]isoquinoline-1,3-dione
Canonical SMILESCOc1cc2cnc3c(c2cc1OC)C(=O)NC3=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.37
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P49840 GSK3A Homo sapiens Human PF00069 7.1 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.9 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.1 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.0 Ki ChEMBL