Molecule Details
InChIKeyKTMJHDICOAOUQM-SFHVURJKSA-N
Canonical SMILESNC1=N[C@](CF)(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)Cn2nncc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.26
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y5Z0 BACE2 Homo sapiens Human PF00026 8.3 IC50 ChEMBL;BindingDB
P56817 BACE1 Homo sapiens Human PF00026 8.2 IC50 ChEMBL;BindingDB