Molecule Details
InChIKeyKSUDUUBCXJUFRL-SFHVURJKSA-N
Compound Name6-amino-7-(4-phenoxyphenyl)-9-[(3S)-1-prop-2-enoylpiperidin-3-yl]purin-8-one
Canonical SMILESC=CC(=O)N1CCC[C@H](n2c(=O)n(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Homologous
Avg pChEMBL8.17
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 8.4 Kd ChEMBL
Q06187 BTK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 8.4 Kd ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 8.3 Kd ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 8.3 Kd ChEMBL
P07947 YES1 Homo sapiens Human PF07714 PF00017 PF00018 8.3 Kd ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 8.2 Kd ChEMBL
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 8.2 Kd ChEMBL
P42680 TEC Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 8.2 Kd ChEMBL
O43353 RIPK2 Homo sapiens Human PF00619 PF07714 8.2 Kd ChEMBL
P41240 CSK Homo sapiens Human PF07714 PF00017 PF00018 8.2 Kd ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 7.7 Kd ChEMBL
Q13882 PTK6 Homo sapiens Human PF07714 PF00017 PF00018 7.6 Kd ChEMBL