Molecule Details
InChIKeyKSMZEXLVHXZPEF-UHFFFAOYSA-N
Canonical SMILESCOc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ccnc2cc1OCC1(N)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.32
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB11885
Drug NameAnlotinib
CAS Number1058156-90-3
Groups investigational
ATC Codes nan
DescriptionAnlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.

Categories: Heterocyclic Compounds, Fused-Ring
Cross-references: CHEMBL4303201 ChemSpider: 45743493 PubChem:25017411 PubChem:347828221 ZINC: ZINC000117924202
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 9.7 IC50 ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.9 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P12931 SRC Proto-oncogene tyrosine-protein kinase Src inhibitor targets