Molecule Details
| InChIKey | KRTIYQIPSAGSBP-ZACQAIPSSA-N |
|---|---|
| Canonical SMILES | C[C@@H](C(=O)Nc1ccc(Cl)cc1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.38 |
| Source | ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB14986 |
|---|---|
| Drug Name | Linrodostat |
| CAS Number | 1923833-60-6 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Linrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants). |
Categories: Acetates Acids, Acyclic Amides Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring
Cross-references: ChemSpider: 58828674 PDB: H7P
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P14902 | IDO1 | Indoleamine 2,3-dioxygenase 1 | inhibitor | targets |